Should the qualitative serum pregnancy test be considered obsolete?
نویسندگان
چکیده
Qualitative and quantitative serum human chorionic gonadotropin (hCG) tests are used to diagnose pregnancy. We assessed physicians' perceptions and compared turnaround times (TATs) and performance characteristics of both tests. We surveyed 1,058 physicians about their perceptions of hCG tests. Seven months of TAT data were analyzed. hCG was measured in all qualitative samples. Pregnancy status was determined by chart review. Of the physicians surveyed, 183 responded. Forty-nine percent preferred qualitative over quantitative serum tests for determining pregnancy status. Physicians were willing to wait 45 minutes for results from either test. Qualitative tests are performed faster than quantitative tests, but TATs were not significantly different when sample transport time was considered. The negative predictive value of both tests was 99.9%. Qualitative serum hCG testing could be replaced by quantitative hCG tests, but there is no clear advantage to doing so.
منابع مشابه
مقایسه حساسیت و ویژگی آزمایشهای کیفی ادرار با روش ایمونوآنزیماتیک سریع در تشخیص بارداری
Background and Aim: Early diagnosis of pregnancy is very important to prevent fetal damage due to specific drug consumption and high-risk behaviors. The objective of this study was to compare the sensitivity and specificity of quantitative agglutination pregnancy tests in urine and rapid β hCG immunoenzymatic assay test in serum as a gold standard. Materials and Methods: This cross-sectional st...
متن کاملAn algorithm for testing and reporting serum choriogonadotropin at clinically significant decision levels with use of "pregnancy test" reagents.
We present an algorithm for monitoring the concentration of human choriogonadotropin (hCG) in serum at various clinical decision levels with use of fast, simple, and cost-effective qualitative pregnancy test reagents for hCG in serum. Based on correlation between laboratory data and clinical observations described in the literature, the following concentrations of hCG in serum can be considered...
متن کاملCorrelation of pregnancy outcome with quadruple screening test at second trimester
Background: Abnormal levels of the markers AFP, hCG, and uE3 could be useful in predicting adverse pregnancy outcomes. This study was designed to determine the correlation between second trimester maternal serum markers and adverse pregnancy outcome (APO). Methods: In this historical cohort study, we randomly followed 231 obstetric patients with quadruple screening test in 14-18 weeks of ges...
متن کاملUtility of Maternal Serum Analyte Screening in the Era of Cell-free Fetal DNA
Background: To determine whether in the era of cell-free fetal DNA (cffDNA), first and second trimester maternal serum analytes will be obsolete or whether they have a role in predicting adverse pregnancy outcomes. Methods: Retrospective cohort study using maternal serum analyte results from first trimester and sequential screening tests from 1/2002 to 12/2012. Abnormal serum analytes included ...
متن کاملThe prevalence of adverse obstetric outcomes follow of an abnormal maternal serum AFP and NTDs screen positive group
Introduction: Prenatal maternal serum AFP screening tests have some inherent false positive and false negative results. For NTDs Screening test (FTS) false positive rate (FPR) is about 1% and false negative rate (FNR) is 20%. A false positive result encourages by Anomaly scan and invasive diagnostic procedures (that poses lots of stress on women, too), while a false negative result lead to a N...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- American journal of clinical pathology
دوره 137 2 شماره
صفحات -
تاریخ انتشار 2012